Semler Scientific, Inc., founded in 2007, is a healthcare technology company headquartered in Santa Clara, California. The company specializes in developing and marketing innovative products and services that support the early detection and treatment of chronic diseases. Its flagship product, QuantaFlo®, is a rapid point-of-care test that measures arterial blood flow in the extremities, aiding in the diagnosis of peripheral arterial disease. In May 2024, Semler adopted Bitcoin as its primary treasury reserve asset, becoming the second U.S. public company to do so. By July 31, 2025, the company held 5,021 Bitcoin, reflecting a strategic shift towards cryptocurrency investments. However, in April 2025, Semler agreed to a $29.75 million settlement with the U.S. Department of Justice over claims related to its QuantaFlo device, highlighting the company’s complex regulatory landscape.
